Facile access to pyridinium-based bent aromatic amphiphiles: nonionic surface modification of nanocarbons in water

• Lorenzo Catti,
• Shinji Aoyama and
• Michito Yoshizawa

Beilstein J. Org. Chem. 2024, 20, 32–40, doi:10.3762/bjoc.20.5

• )m was roughly estimated to be 0.1 mg mL−1. The DLS measurement of (PA-Im)n·(C60)m displayed an average particle diameter of ≈2 nm, which, in combination with molecular modeling, indicated a noncovalent surface functionalization of a single C60 molecule by five PA-Im amphiphiles (Figure 4d,e

Exfoliated black phosphorous-mediated CuAAC chemistry for organic and macromolecular synthesis under white LED and near-IR irradiation

• Azra Kocaarslan,
• Zafer Eroglu,
• Önder Metin and
• Yusuf Yagci

Beilstein J. Org. Chem. 2021, 17, 2477–2487, doi:10.3762/bjoc.17.164

• has set a milestone as a new and effective method for the synthesis of macromolecules [11]. Initiation of this reaction photocatalytically provides many advantages for the synthetic methodologies including bioconjugation, labeling, surface functionalization, dendrimer synthesis, polymer synthesis, and

Optical detection of di- and triphosphate anions with mixed monolayer-protected gold nanoparticles containing zinc(II)–dipicolylamine complexes

• Lena Reinke,
• Julia Bartl,
• Marcus Koch and
• Stefan Kubik

Beilstein J. Org. Chem. 2020, 16, 2687–2700, doi:10.3762/bjoc.16.219

• behaved qualitatively similar in that they only responded to hydrogenphosphate, diphosphate, and triphosphate, the anion concentrations necessary to induce visual changes depended sensitively on the extent of the surface functionalization. NP4-Zn with the lowest amount of surface-bound recognition units

• detrimental for the sensitivity, maybe because efficient crosslinking required a large number of anions to overcompensate potential repulsive interactions between unused surface-bound zinc complexes when the degree of the surface functionalization was high. However, the weak and unspecific response of NP35-Zn

• probes is that they not only contained the ligand responsible for the substrate recognition but an additional ligand that allowed controlling the number of active residues on the surface. This structural feature allowed us to assess how the degree of surface functionalization affects the sensitivity, and

Design and synthesis of multivalent α-1,2-trimannose-linked bioerodible microparticles for applications in immune response studies of Leishmania major infection

• Chelsea L. Rintelmann,
• Tara Grinnage-Pulley,
• Kathleen Ross,
• Daniel E. K. Kabotso,
• Angela Toepp,
• Anne Cowell,
• Christine Petersen,
• Balaji Narasimhan and
• Nicola Pohl

Beilstein J. Org. Chem. 2019, 15, 623–632, doi:10.3762/bjoc.15.58

• recognition. To allow for both surface functionalization of this glycan to the bioerodible microparticles and conjugation of the fluorophore, two amine handles would be necessary (Figure 3). The design would also benefit from the development of a more efficient synthesis of the mannose oligomer sidechain

• core allowed for various potential linkage options in addition to providing the amine handle for microparticle surface functionalization. Unfortunately, the sterically encumbered tertiary amine of the dendrimer prevented simple coupling of commercially available Nα-TAMRA-Nε-Teoc-L-lysine to the

Rational design of boron-dipyrromethene (BODIPY) reporter dyes for cucurbit[7]uril

• Mohammad A. Alnajjar,
• Jürgen Bartelmeß,
• Robert Hein,
• Pichandi Ashokkumar,
• Mohamed Nilam,
• Werner M. Nau,
• Knut Rurack and
• Andreas Hennig

Beilstein J. Org. Chem. 2018, 14, 1961–1971, doi:10.3762/bjoc.14.171

• . This includes indicator displacement assays with favourable absorption and emission wavelengths in the visible spectral region, fluorescence correlation spectroscopy, and noncovalent surface functionalization with fluorophores. Keywords: BODIPY; cucurbituril; fluorescence; pH; photoinduced electron

• specific host–guest binding of 5 to CB7 on the surface, which suggests the use of 5 for straightforward surface functionalization to create nanophotonic devices as well as for multimodal surface group quantifications, e.g., using their optical properties for fluorescence and their fluorine heteroatom for X

• of fluorescent host–guest complexes, for example, indicator displacement assays with absorption and emission wavelengths in the visible spectral region, fluorescence correlation spectroscopy, and noncovalent surface functionalization with fluorophores. Furthermore, the strategy is similarly

Sulfamide chemistry applied to the functionalization of self-assembled monolayers on gold surfaces

• Loïc Pantaine,
• Vincent Humblot,
• Vincent Coeffard and
• Anne Vallée

Beilstein J. Org. Chem. 2017, 13, 648–658, doi:10.3762/bjoc.13.64

• view of the SAMs hydrolysis. General strategy for surface functionalization based on sulfamide chemistry. Synthesis of the reference molecule sulfamide 1. Assignment of the vibrational modes probed by PM-IRRAS. Experimental (XPS) and theoretical characteristic ratios of the 4-ATP SAM, the 4-ATP SAM

Synthesis of tripodal catecholates and their immobilization on zinc oxide nanoparticles

• Franziska Klitsche,
• Julian Ramcke,
• Julia Migenda,
• Andreas Hensel,
• Tobias Vossmeyer,
• Horst Weller,
• Silvia Gross and
• Wolfgang Maison

Beilstein J. Org. Chem. 2015, 11, 678–686, doi:10.3762/bjoc.11.77

• = hydroxybenzotriazole; TFA = trifluoroacetic acid, KOTMS = potassium trimethylsilanolate, DIEA = N,N-diisopropylethylamine. Synthesis of tripodal catecholate platforms 11 and 13 for surface functionalization. Supporting Information Supporting Information File 192: Experimental procedures, additional analytical data

Functionalized branched EDOT-terthiophene copolymer films by electropolymerization and post-polymerization “click”-reactions

• Miriam Goll,
• Adrian Ruff,
• Erna Muks,
• Felix Goerigk,
• Beatrice Omiecienski,
• Ines Ruff,
• Rafael C. González-Cano,
• Juan T. Lopez Navarrete,
• M. Carmen Ruiz Delgado and
• Sabine Ludwigs

Beilstein J. Org. Chem. 2015, 11, 335–347, doi:10.3762/bjoc.11.39

• films from water contact angles of 140° down to 40°. Keywords: band-gap engineering; “click”-chemistry; conducting polymers; electropolymerization; Raman spectroscopy; surface functionalization; Introduction The many different applications of conducting polymers demand for tailored properties

Detonation nanodiamonds biofunctionalization and immobilization to titanium alloy surfaces as first steps towards medical application

• Juliana P. L. Gonçalves,
• Afnan Q. Shaikh,
• Manuela Reitzig,
• Daria A. Kovalenko,
• Jan Michael,
• René Beutner,
• Gianaurelio Cuniberti,
• Dieter Scharnweber and
• Jörg Opitz

Beilstein J. Org. Chem. 2014, 10, 2765–2773, doi:10.3762/bjoc.10.293

• evaluation of the surface functionalization of DND can be proved by a qualitative analysis from the Figure 2 and Figure 3. The characteristic absorptions of some functional groups is directly related with the success of the synthesis, which are particularly observed on the assignments of the silane groups

• functionalized with the phosphate group after the silanization process. These results indicate that the surface functionalization of DND is one important parameter for successful adsorption and immobilization on titanium alloy substrate. Another crucial parameter is to achieve a stable suspension of nanodiamonds

Theoretical study of the adsorption of benzene on coinage metals

• Werner Reckien,
• Melanie Eggers and
• Thomas Bredow

Beilstein J. Org. Chem. 2014, 10, 1775–1784, doi:10.3762/bjoc.10.185

• benzene on the M(111), M(100) and M(110) surfaces of the coinage metals copper, silver and gold. The benzene molecule was selected because it is a building block of many organic compounds that are used for surface functionalization. As mentioned above the binding between the metal and the adsorbate is

Photoswitchable precision glycooligomers and their lectin binding

• Daniela Ponader,
• Sinaida Igde,
• Marko Wehle,
• Katharina Märker,
• Mark Santer,
• David Bléger and
• Laura Hartmann

Beilstein J. Org. Chem. 2014, 10, 1603–1612, doi:10.3762/bjoc.10.166

• functionalization was monitored by SPR. Photoswitching of the glycooligomers was realized either ex situ prior to surface functionalization or in situ by direct irradiation of the functionalized chip. The equilibrium constant KD was obtained by fitting the obtained binding values at the turning point between

• values of refractive index determined via SPR on the glycooligomer functionalized chip, we can assume a similar degree of surface functionalization for all switched and non-switched glycooligomers (see Supporting Information File 1). Since all glycooligomers were attached directly via their free N

Polyglycerol-functionalized nanodiamond as a platform for gene delivery: Derivatization, characterization, and hybridization with DNA

• Li Zhao,
• Yuki Nakae,
• Hongmei Qin,
• Tadamasa Ito,
• Takahide Kimura,
• Hideto Kojima,
• Lawrence Chan and
• Naoki Komatsu

Beilstein J. Org. Chem. 2014, 10, 707–713, doi:10.3762/bjoc.10.64

• further surface functionalization to add more functions to ND [14]. As for gene delivery, on the other hand, DNA was immobilized on the surface of nanoparticles mostly by electrostatic attraction between the negative charge of DNA and the positive charge on the surface of the nanoparticle [15]. In the

Towards a biocompatible artificial lung: Covalent functionalization of poly(4-methylpent-1-ene) (TPX) with cRGD pentapeptide

• Lena Möller,
• Christian Hess,
• Jiří Paleček,
• Yi Su,
• Axel Haverich,
• Andreas Kirschning and
• Gerald Dräger

Beilstein J. Org. Chem. 2013, 9, 270–277, doi:10.3762/bjoc.9.33

• plasma treatment with nitrene insertion is a protocol of general importance for the functionalization of biomedical materials based on hydrocarbon-derived polymers. The importance of developing strategies for this kind of copper-free surface functionalization reported here was recently also demonstrated